According to the Lancet's latest Global Burden of Disease report, while cancer incidence and mortality rates are declining globally, India is experiencing an increase. India is projected to see an estimated 1.5 million new cancer cases and over 1.2 million deaths by 2023.

Key findings on the global state of cancer

¨     Global incidence increases: The global cancer incidence rate has declined from 220.6 cases per 100,000 population in 1990 to 205.1 in 2023 and is projected to reach 192.9 by 2025. However, population growth and aging are expected to cause a sharp increase in total cancer cases and deaths by 2050.

¨     Trends in cancer rates: The cancer incidence rate in India increased from 84.8 per 100,000 population in 1990 to 107.2 in 2023, while the mortality rate increased from 71.7 to 86.9 per 100,000 during the same period.

¨     Disproportionate disease burden on low- and middle-income countries: The study warns that more than half of new cancer cases and two-thirds of deaths are estimated to occur in low- and middle-income countries (LMICs) like India.

¨     ​​Modifiable risk factors: Globally, approximately 42% of cancer deaths are linked to modifiable risk factors such as tobacco, alcohol, unhealthy diet, and infections. In India, the share of deaths related to these factors could be as high as 70%.

¨     Future Predictions: According to the report, by the year 2050, approximately 30.5 million new cancer cases are expected worldwide, while cancer deaths are expected to increase by 75% to reach 18.6 million. The leading causes of cancer deaths in India are breast, lung, esophagus, mouth, cervix, stomach, and colon cancers.

What factors are responsible for the increase in cancer cases in India?

1.     Changing Demographics - Aging: Due to the increase in both life expectancy and population in India, the number of elderly people is increasing rapidly, which is also increasing the population vulnerable to cancer. As a result, despite the rate per 100,000 population remaining stable, the total number of cases is increasing. Longer life expectancy has increased the prevalence of non-communicable diseases, of which cancer is a major one.

2.     Adoption of Unhealthy Lifestyles: In India, high tobacco use, unhealthy diets, sedentary lifestyles, and alcohol consumption increase the risk of lung, mouth, throat, esophagus, pancreas, and liver cancers.

3.     National Health System Deficiencies: Most cancers are diagnosed late (in stage 3 or 4). Lack of oncologists and radiotherapy machines, as well as high health expenditure, leads to delayed treatment, poor outcomes, and increased cancer mortality.

4.     Carcinogenic Environmental Exposure: Outdoor air pollution (PM2.5, a Class I carcinogen), indoor air pollution from solid fuels, and industrial and chemical exposure increase the risk of lung cancer.

5.     Economic Hardship from Treatment: The high cost of cancer treatment, surgery, chemotherapy, and radiotherapy limits access to health care. This leads many people to delay or avoid treatment, leading to increased cancer incidence and mortality.

6.     Rising Infection-Linked Cancers: Infections contribute significantly to the rise in cancer cases, including Human Papillomavirus (HPV), cervical cancer, hepatitis B and C viruses (liver cancer), and H. Pylori (stomach cancer).