Jawaharlal Nehru University (JNU) scientists have identified a promising vaccine candidate against malaria.
It would help in more effective prevention and treatment strategies against malaria.
Scientists have identified a novel PHB2-Hsp70A1A receptor ligand pair.
The parasite protein PHB2 is therefore a potent vaccine candidate.
The presence of PfPHB2 antibodies was detected in active malaria patient from the Tripura region.
The PfPHB2 antibodies will be a turning point towards malaria therapeutic development.
The scientists have found that PfPHB2 protein which is found on the merozoite surface. It will interact with the red blood cell surface heat-shock protein Hsp70A1A.
Prohibitins are a family of proteins that will play important role in various cellular processes.
This research has been published in the iScience journal by Cell Press.
